Monday, September 23, 2019
Business Writing Essay Example | Topics and Well Written Essays - 250 words
Business Writing - Essay Example This minimizes disputes, since unrecorded conversations can be distorted or forgotten, and can easily be retrieved when categorized and stored properly. Although a memo is an informal letter, it should still indicate relevant information so that receiving parties can act accordingly. Such information includes the addressees of the memo, date, name of the sender and most importantly, the subject of the matter. A memo can be distributed internally or posted in the company's bulletin board. On the other hand, a business letter is very formal because more likely than not, it is intended for external parties. As such, the format of a letter differs greatly from that of a memo. A business letter includes the recipient's name and address, date, salutation, subject, body of the letter, complimentary close and signature of the sender. Sometimes, an enclosure is included if required. In addition, a business letter must be printed using the company's letterhead. The writing method used in a business letter should be formal, polite and serious to indicate the level of professionalism. The content of a business letter should also be clear and concise. A business letter is usually sent by post or courier.
Sunday, September 22, 2019
The development of new reproductive technologies Essay Example for Free
The development of new reproductive technologies Essay Explain some of the religious and moral issues relevant to the development of new reproductive technologies. [35] The development of new reproductive technologies have revolutionised the way society views infertility. However, many object to methods such as IVF, cloning, ICSI and PGD for moral and religious reasons. In examining these issues, a good place to start is IVF. IVF ââ¬â in vitro fertilisation ââ¬â is one of the most commonly used reproductive technologies. This method bypasses the need for intercourse to conceive; embryos are instead created in a lab and implanted into a mother. It can either use gametes from two parents, or in the case of a homosexual couple some of the material will be donated. From a human-rights perspective everyone has the right to a family life, which some interpret to mean a right to IVF. However, even from a purely secular point of view there are moral problems with IVF. For example, the new ICSI method bypasses many of the bodys natural defences for weeding out unfit sperm and therefore the child is at a higher risk of genetic abnormalities. Additionally, some feminists view reproductive technology with suspicion. Feminists refer to a `pro-natalist ideology prevalent in Western society, whereby women are encouraged to believe that their fulfilment and happiness depends upon their being able to bear children. They fear women may be coerced into IVF. The main issue that Christians would have with IVF is that many embryos are created and then destroyed. More embryos are produced in order to increase the chances of successful implantation, but in the UK you cannot use more than two embryos per IVF cycle. This creates spare embryos that are discarded, experimented upon or frozen for later use. The majority of Christians believe that life and personhood are intertwined, and both begin at conception. Christians believe in the sanctity of life, meaning that all human life is created in Godââ¬â¢s image and has intrinsic worth. The most important verse they turn to is part of the Decalogue: ââ¬Å"do not kill.â⬠Moreover, Psalm 139 says, ââ¬Å"you knit me together in my motherââ¬â¢s womb.â⬠Therefore the discarding of spare embryos is murder of an innocent life. As with any issue, denominational opinions differ. The Roman Catholic Church defends traditional family structures and view IVF as unnatural. They published a document in 1987called Respect for Human Life in its Origin and the Dignity of Procreation. This emphasised the principles concerning the sanctity of life laid down much earlier in the Papal Encyclical, Humanae Vitae of 1968. In summary it claimed that children were a gift from God and not a commodity, and the proper place for children is within marriage. The church has expressed fears that IVF trivialises intercourse. Protestant churches tend to take a more lenient view. For example, the Free Presbyterian Church accepts IVF provided that the couple are married, spare embryos are not created and no donors are used. Both the Methodist Church and the Church of England are quite positive about all forms of IVF and even permit research on spare embryos up to 14 days old because it can be of great help to doctors researching genetic diseases, although embryos should not be created solely for this purpose. Other more drastic forms of reproductive technology pose a bigger problem for the churches. The successful cloning of Dolly the Sheep opened up a debate on the potential of human cloning and saviour siblings. Reproductive cloning would devalue individuality and result in negative psychological effects in the cloned person. Cloned animals tend to have a shorter lifespan and there is a genuine fear that a sub-class of humans could be produced in order for their organs to be harvested. This commodification of life sounds like science fiction, but according to Paul Ramsey it is a real threat. Cloning also removes the need for a male. In the case of Dolly, she had three ââ¬Ëmothersââ¬â¢: one provided the egg, another the DNA and a third carried the cloned embryo to term. The embryo was given an electric shock in order to begin the division process. For Christians this disrupts Godââ¬â¢s design for reproduction and parenthood. The only form of cloning that some churches would permit is therapeutic cloning, when a personââ¬â¢s stem cells can be used to produce organs that are an exact match. Mary Seller, a member of the Church of Englands Board of Social Responsibility, states, Cloning, like all science, must be used responsibly. Cloning humans is not desirable.â⬠Furthermore, another key form of reproductive technology is PGD pre-implantation genetic diagnosis. This process can eliminate genetic diseases by selection (negative therapy) and can also alter the genes to ââ¬Ëimproveââ¬â¢ an embryo (positive therapy). It can be used to prevent suffering for both the child and parents. Moral objects are raised because, just like IVF, negative therapy involves fertilising several embryos with the intent of destroying those with the disease. This is dehumanising to disabled people, because it suggests that society would be better off without them. Positive therapy takes it to another level, and could result in a class of humans that are genetically modified for maximum health, intelligence and appearance. This destroys individualism and Christians refer to it as, ââ¬Å"playing God.â⬠According to the Free Presbyterian Church, ââ¬Å"remember that each time cells are harvested for the treatment of someone who is sick, a new and sacred lif e is callously ended.â⬠Moving on, reproductive technology can be evaluated according to traditional ethical principles. Starting with Utilitarianism, Patrick Steptoe is quoted as stating that It is a fact that there is a biological desire to reproduce.â⬠If this is the case, then the maximum amount of happiness for the greatest amount of people will be achieved if they are able to reproduce, even if they need IVF or other interventions. Since successful IVF treatment will bring an enormous amount of happiness utilitarians are in agreement with such treatments. In the case of an infertile couple the utilitarian will look at the options available and strive towards to goal of conception. Likewise, if PGD and cloning can help alleviate human suffering it will be supported by utilitarians. Situation ethics bases the morality of an action on the circumstances that surround it. The only underlying principle is that we should always choose the most loving course of action, and there is no absolute morality. Whether an infertile couple should have access to IVF is based entirely on their individual situation. Natural law, on the other hand, is not so accepting. It is similar to the view the Roman Catholic Church takes. IVF and other technologies are unnatural and therefore immoral. Some criticise this theory because they claim that it is no more unnatural then the countless other forms of human intervention such as when we have an operation. Ultimately, reproductive technology causes us to rethink our views on family, marriage, sex and what makes a mother. Regardless of their views, Christians should be compassionate towards those suffering from the effects of infertility. You cannot understand their situation unless you have experienced it personally.
Saturday, September 21, 2019
Effect of Buprenorphine on Postoperative Pain Levels
Effect of Buprenorphine on Postoperative Pain Levels Katelyn Shultz Nurse Anesthesia ABSTRACT In recent years, buprenorphine has become an increasingly popular choice for managing opioid dependence; however, buprenorphineââ¬â¢s unique mechanism of action can make treating acute pain more complicated. In opioid-dependent patients managed with buprenorphine, would continuing buprenorphine therapy during the perioperative period affect postoperative pain levels? The research method for this study is a formal literature review. I predict that continuing buprenorphine throughout the perioperative period will improve postoperative pain levels in opioid-dependent patients maintained on buprenorphine. INTRODUCTION In recent years, buprenorphine has become an increasingly popular choice in the treatment of opioid dependence. Even though it is a partial mu agonist, buprenorphine is known to have high mu-receptor affinity. When buprenorphine is continued throughout the perioperative period, this property may reduce the effectiveness of other full mu agonist opioids. As a result, this pharmacological trait introduces an obstacle for successful treatment of acute surgical pain in the patient taking chronic buprenorphine. The clinician must choose the best option for this patient, to continue or discontinue buprenorphine therapy during the perioperative period. BACKGROUND AND SIGNIFICANCE It is imperative to establish evidence-based practice guidelines regarding the best method of acute pain management for patients taking chronic buprenorphine. As buprenorphine use increases, healthcare providers will encounter opioid-dependent patients taking chronic buprenorphine with higher frequency in the surgical setting.1 Although the positive outcomes of buprenorphine use are comprehensively researched and well documented, the evidence regarding the perioperative continuation or suspension of buprenorphine is limited and inconsistent. As a result, prescribers may avoid buprenorphine altogether, ultimately preventing more patients from receiving a potentially superior treatment. Perioperative is defined as the phase immediately prior, during, and immediately after a surgical procedure. Postoperative period is defined as the phase after a surgical procedure is performed. Buprenorphine maintenance therapy (BMT) is defined as a sustained dose of buprenorphine taken by an opioid-dependent patient for an indefinite period of time. Methadone maintenance therapy (BMT) is defined as a sustained dose of methadone taken by an opioid-dependent patient for an indefinite period of time. Full mu opioid agonists activate mu receptors until a maximum effect is reached or the receptor is fully activated. Methadone, morphine, and oxycodone are examples of full mu agonists. Partial mu opioid agonists bind to receptors and partially activate them, but not to the same degree as do full agonists. Partial mu agonists can also displace full mu agonists from receptors. Buprenorphine is a partial mu agonist. Patient-controlled analgesia (PCA) is any method of allowing a person in pai n to administer their own pain relief. METHODS The research method for this study was a formal literature review. The purpose of this study was to answer the question, in opioid-dependent patients managed with buprenorphine, would continuing buprenorphine therapy during the perioperative period affect postoperative pain levels? I searched the database SuperSearch. The key terms for this search were (pain management OR treatment), buprenorphine, and (perioperative OR intraoperative OR postoperative) using the Boolean operator AND. I limited results to peer-reviewed academic journal articles published in English from 2004-2014. Initial results were refined using the inclusion criteria of patients maintained on buprenorphine therapy prior to surgery and perioperative pain management, and the exclusion criteria of animal studies and buprenorphine administration techniques: epidural, intrathecal, perineural, subcutaneous, and transdermal. REVIEW OF THE LITERATURE The purpose of these studies is to examine perioperative acute pain management in opioid-tolerant patients taking BMT. The type of studies include a retrospective cohort study, literature reviews, and case reports examining a population of people taking chronic buprenorphine. Buprenorphine may be a more preferable method than methadone for chronic opioid replacement therapy. The use of buprenorphine has been associated with improvement in education, social life, and toxicological conditions when compared to methadone.1 Buprenorphine is also perceived to have less adverse effects and social stigma than methadone.2 In addition, buprenorphineââ¬â¢s full opioid agonist effects are lower compared to methadone, improving its safety profile.3 Buprenorphine may also induce less hyperalgesia than full agonists, although this has yet to be confirmed.2 In support of this statement, however, Koppert et al4 found that the antihyperalgesic effects of buprenorphine were stronger and of longer duration as compared with the pure mu receptor agonist studied in the same model. Though some researchers recommend a transition from buprenorphine to a full mu agonist preoperatively, an interruption in BMT is not ideal. A drug holiday or transition to other chronic opioids, such as methadone, prior to surgery may lead to simplified sedation techniques; however, it is time consuming and unnecessary, and alternatives should be considered.1 It is best that patients with opioid dependence be in some early withdrawal before initiating treatment with buprenorphine.5 As a result, when a patient transitioned to methadone prior to surgery returns to their previous dose of buprenorphine postoperatively, withdrawal may occur.1 Additionally, for patients switched from BMT to MMT preoperatively, methadone must be ceased for at least 36 hours and the patient should experience mild withdrawal symptoms before buprenorphine is restarted.6 In contrast to these recommendations, the retention of buprenorphine was found to be better in heroin addicts with less morbidity if buprenorp hine was not rapidly withdrawn, but continued for up to 350 days.5 When chronic buprenorphine doses were continued throughout perioperative period, patients were able to achieve good pain control with additional opioids and/or additional buprenorphine doses. In a small series of 5 patients, adequate pain control was achieved when other full mu agonist opioids were given as needed in addition to the patientââ¬â¢s usual daily dose of buprenorphine.7 In another study,8 the patient achieved adequate pain control on postoperative day 1 and 2 with a total daily buprenorphine dose of 72 mg, and was able to successfully and comfortable taper to her baseline dose of 24 mg/d by day 11. Furthermore, Jones et al9 reported the buprenorphine-managed patient scored 0 out of 10 on all 6 post morphine-PCA pain assessments, and 0 to 5 out of 10 on all post discharge pain assessments while taking buprenorphine and oxycodone/acetaminophen. Only 1 study10 reported severe postoperative pain control with the continuation of buprenorphine during the perioperative period. The study10 highlighted a case report for one patient with Type I Chiari malformation receiving buprenorphine for chronic pain who underwent two identical surgical procedures. For the first procedure, the patientââ¬â¢s usual dose of buprenorphine was continued throughout the perioperative period, and a full mu agonist was used for postoperative pain.10 The patient reported severe postoperative pain after this procedure.10 This information is limited, however, by self-report. No documentation was obtained from the outside hospital where the first procedure was performed.10 The author is a representative for the hospital where the second procedure was performed.10 For the second procedure, the patientââ¬â¢s buprenorphine was discontinued 5 days prior to surgery, and the patient was transitioned to a full opioid agonsist.10 Again, the patientââ¬â¢s p ostoperative pain was managed with a full opioid receptor agonist.10 Though the patient reported acceptable pain control on postoperative day 1, the patientââ¬â¢s pain was reported at 7 to 8/10 immediately after surgery.10 Although some researchers suggest that buprenorphine decreases full mu agonist opioidââ¬â¢s effectiveness, many found the addition of full mu agonists in the perioperative setting to be beneficial for buprenorphine-maintained patients. Buprenorphineââ¬â¢s long half-life, high opioid receptor affinity, partial agonist activity, and slow dissociation from the mu receptor may reduce analgesic effectiveness of full mu opioid agonists; however, the data does not support the commonly held belief that high dose BMT will interfere with the activity of full mu agonist opioids given for the relief of postoperative pain.6 Morphine has been shown to be an effective breakthrough medication to control postoperative pain in buprenorphine-maintained patients.11 In a retrospective cohort study, Macintyre et al6 confirmed BMT patients who were not given buprenorphine the day after surgery had significantly higher (P=.02) PCA morphine equivalent requirements in the first 24 hours after surgery co mpared with those who were given their usual dose of buprenorphine. In another uncontrolled comparison of BMT and MMT groups, researchers12 found that the first 24 hour postoperative PCA opioid requirements were lower for BMT and MMT groups when maintenance drugs were continued compared with BMT and MMT groups whose maintenance drugs had been ceased perioperatively. Despite the fact that one report6 showed a reduction in whole brain mu receptor availability with high doses of buprenorphine, several studies demonstrated that there is no ceiling effect for the analgesic properties of buprenorphine, only for an opioidââ¬â¢s euphoric effects and respiratory depression. It has been shown that buprenorphine attenuates the effects of additional opioid agonists rather than exert an absolute ceiling effect, and this minimizes euphoric properties of concurrently administered opioids and discourages the likelihood of ongoing opioid abuse.2 Macintyre et al6 also revealed that PCA opioid requirements were lower when BMT was continued after surgery, implying that buprenorphine may still have analgesic effects. Walsh et al13 documented no ceiling effect for analgesia in patients that received sublingual buprenorphine up to 32 mg. As there are no additional opioid effects with escalating doses, this property limits abuse potential and minimizes respiratory d epression with high doses.2 In a study of 20 volunteers, Dahan et al14 confirmed buprenorphineââ¬â¢s ceiling effect on respiratory depression, but not on its analgesic effects. As buprenorphine demonstrates a ceiling effect for respiratory depression, it is safe for outpatient use in high doses; however, when used in conjunction with sedatives, a synergistic effect in respiratory depression may occur. One case report8 verified that a high daily dose of buprenorphine (72 mg) was safely used as an outpatient dose, though no other respiratory depressants were used. Combining benzodiazepines with buprenorphine can exert a synergistic effect on the central nervous system resulting in sedation and respiratory depression.11 Deaths from buprenorphine have been reported, but it has been suggested that these deaths predominantly occurred as a result of prolonged respiratory depression when administered with sedatives, particularly benzodiazepines.2 There is no consensus on recommendations regarding acute pain management for buprenorphine-maintained patients presenting to the perioperative setting and more research is needed. Some articles2,5,11 recommend the cessation of buprenorphine preoperatively and conversion to a full opioid agonist throughout the perioperative period. Conversely, others1,2,5,8 demonstrate successful pain management in the acute pain setting with divided daily and/or additional doses of buprenorphine. The majority of researchers,2,3,5,9,11,15 however, support the continuation of usual buprenorphine maintenance therapy with the addition of full mu agonist opioid analgesics for effective perioperative pain control. There are no recommendations based on high level evidence,15 and data is sparse regarding the best method of treatment for pain in the opioid-dependent population.5 Regardless of point of view, most studies agree that additional research regarding acute pain management for patients taking chronic buprenorphine is urgently needed.5,10,11 DISCUSSION It is clear that buprenorphine is a better alternative than methadone for the treatment of opioid dependence. Associated with less respiratory depression and a lower abuse profile, buprenorphine is a safer medication than methadone and can be used without difficulty in outpatient therapy. With a long half-life and slow dissociation time, buprenorphine can also be dosed less frequently. Buprenorphine has also been known to cause less side effects than methadone. All of these features can increase adherence to opioid replacement therapy by allowing the opioid-dependent patient a less restrictive lifestyle. There is a great deal of uncertainty regarding the best method for treating acute surgical pain in patients taking chronic buprenorphine. There are multiple recommendations regarding perioperative pain management and BMT; however, most methods are developed from the results of uncontrolled studies with very small sampling sizes. Consequently, few are able to establish actual significance in their findings. Without concrete evidence, concise standard recommendations are difficult to establish. CONCLUSION Based on the literature, the continuation of BMT during the perioperative period with the addition of short acting full mu opioids and/or additional buprenorphine doses is the best approach to treating acute surgical pain. For future research, more controlled studies with larger sample sizes are needed in order to confirm the best method of acute pain management in the surgical setting for patientââ¬â¢s taking chronic buprenorphine. References Wasson M, Beirne O. Buprenorphine therapy: an increasing challenge in oral and maxillofacial surgery. Oral Surg Oral Med Oral Pathol Oral Radiol. 2013;(2):142. Available from: Academic OneFile, Ipswich, MA. Accessed June 3, 2014. Roberts D, Meyer-Witting M. High-dose buprenorphine: perioperative precautions and management strategies. Anaesth Intensive Care. February 2005;33(1):17-25. Available from: MEDLINE, Ipswich, MA. Accessed June 10, 2014. Bryson E, Lipson S, Gevirtz C. Anesthesia for Patients on Buprenorphine. Anesthesiol Clin. January 1, 2010;28(Perioperative Pharmacotherapy):611-617. Available from: ScienceDirect, Ipswich, MA. Accessed June 3, 2014. Koppert W, Ihmsen H, Korber N, et al. Different profiles of buprenorphineinduced analgesia and antihyperalgesia in a human pain model. Pain 2005;118(1ââ¬â2):15ââ¬â22. Cited by: Vadivelu N, Anwar M. Buprenorphine in Postoperative Pain Management. Anesthesiol Clin. January 1, 2010;28(Perioperative Pharmacotherapy):601-609. Available from: ScienceDirect, Ipswich, MA. Accessed June 3, 2014. Vadivelu N, Mitra S, Kaye A, Urman R. Perioperative analgesia and challenges in the drug-addicted and drug-dependent patient. Best Pract Res Clin Anaesthesiol. March 2014;28(1):91. Available from: Supplemental Index, Ipswich, MA. Accessed June 10, 2014. Macintyre P, Russell R, Usher K, Gaughwin M, Huxtable C. Pain relief and opioid requirements in the first 24 hours after surgery in patients taking buprenorphine and methadone opioid substitution therapy. Anaesth Intensive Care. March 2013;41(2):222-230. Available from: Academic Search Premier, Ipswich, MA. Accessed June 3, 2014. Kornfield H, Manfredi L. Effectiveness of full agonist opioids in patients stabilized on buprenorphine undergoing major surgery: a case series. Am J Ther 2010;17:523-528. Cited by: Huxtable C, Roberts L, Somogyi A, Macintyre P. Acute pain management in opioid-tolerant patients: a growing challenge. Anaesth Intensive Care. September 2011;39(5):804-823. Available from: Academic Search Premier, Ipswich, MA. Accessed June 3, 2014. Book S, Myrick H, Malcolm R, Strain E. Buprenorphine for postoperative pain following general surgery in a buprenorphine-maintained patient. Am J Psychiatry. June 2007;164(6)Available from: PsycINFO, Ipswich, MA. Accessed June 3, 2014. Jones H, Johnson R, Milio L. Post-cesarean pain management of patients maintained on methadone or buprenorphine. Am J Addict. May 2006;15(3):258-259. Available from: MEDLINE, Ipswich, MA. Accessed June 3, 2014. Chern S, Isserman R, Chen L, Ashburn M, Liu R. Perioperative Pain Management for Patients on Chronic Buprenorphine: A Case Report. J Anesth Clin Res. October 2012;3(10):1. Available from: Supplemental Index, Ipswich, MA. Accessed June 3, 2014. Vadivelu N, Anwar M. Buprenorphine in Postoperative Pain Management. Anesthesiol Clin. January 1, 2010;28(Perioperative Pharmacotherapy):601-609. Available from: ScienceDirect, Ipswich, MA. Accessed June 3, 2014. Russell R, Usher K, Macintyre PE. A comparison of postoperative opioid requirements and effectiveness in methadone- and buprenorphine-maintained patients. Anaesth Intensive Care. 2011;39:726-727. Cited by: Huxtable C, Roberts L, Somogyi A, Macintyre P. Acute pain management in opioid-tolerant patients: a growing challenge. Anaesth Intensive Care. September 2011;39(5):804-823. Available from: Academic Search Premier, Ipswich, MA. Accessed June 3, 2014. Walsh SL, Preston KL, Stitzer ML, et al. Clinical pharmacology of buprenorphine: ceiling effects at high doses. Clin Pharmacol Ther. 1994;55(5):569ââ¬â80. Cited by: Vadivelu N, Anwar M. Buprenorphine in Postoperative Pain Management. Anesthesiol Clin. January 1, 2010;28(Perioperative Pharmacotherapy):601-609. Available from: ScienceDirect, Ipswich, MA. Accessed June 3, 2014. Dahan A, Yassen A, Romberg R, et al. Buprenorphine induces ceiling in respiratory depression but not in analgesia. Br J Anaesth. 2006;96(5):627ââ¬â32. Cited by: Vadivelu N, Anwar M. Buprenorphine in Postoperative Pain Management. Anesthesiol Clin. January 1, 2010;28(Perioperative Pharmacotherapy):601-609. Available from: ScienceDirect, Ipswich, MA. Accessed June 3, 2014. Huxtable C, Roberts L, Somogyi A, Macintyre P. Acute pain management in opioid-tolerant patients: a growing challenge. Anaesth Intensive Care. September 2011;39(5):804-823. Available from: Academic Search Premier, Ipswich, MA. Accessed June 3, 2014. 1
Friday, September 20, 2019
Right to Free Movement in the European Market
Right to Free Movement in the European Market The philosophy The right to move freely represents one of the fundemental freedoms of the European internal market. This general rule on free movement rights under EC law continues to be developed,[1] either due to member state progression or economic and social demands. Although one of the most panoramic in itââ¬â¢s ideals, the free movement of workers has seen several central legal issues arise on various occassions. But exploration of these central issues must be seen through a consideration of the tensions and interplay between both economic and social aspects of the free movement of people from both inside and outside of the European Union. The free movement of a citizen of the European Unon is seen to contribute to the economic progression of the Community as a whole. In the single market the worker is also a human being exercising their right to live in another state and to take up employment without the risk of discrimination and to improve the standards of living for themsleves, and possibly, their families. But for nationals of a third party cases such as Chen (2004), Baumbast (2002) and Carpenter (2002) have meant that as the spouse or realtive of an EU citizen their entry into the Community is a secure one. Further, gaining the same rights of an EU citizen under Regulation 1612/68 EEC. But this idea of border controls and unfettered freedom of movement within the Community is closely interlinked with the posiiton of the non-EC national, whose right to movement and residence under EC law is limited,[2] as well as the contribtuing effect that the members statesââ¬â¢ attitude has upon their admission.[3] ââ¬Å"Fortress Europeâ⬠Although EC legislation had intended that internal barriers to the four freedoms be eliminated and that only an external barrier (at the borders of the Community) remain, academics have argued that this may not always be so:[4] ââ¬Å"[how] these proposals have been watered down through discussion in member states, in particular in relation to employment, which is an important requisite for the integration of migrants.â⬠[5] Whilst the freedom of the EC worker is guaranteed through Treaty rules and secondary legislation, this does not mean that member states may no longer exercise control over population movements, into and within their territories.[6] But some ECJ case law on Directive 68/360 expressly recognised that member states may have legitimate reasons for wishing to keep account of the population within their terrrtories.[7] The European Union, by using border controls to itââ¬â¢s extremities, has managed ot create a border-free, intra-EU site creating what has been dubbed as ââ¬Å"Communierisationâ⬠of its geographical position. Although the EU has been successful in its pursuit of removing internal barriers to the four freedoms, itââ¬â¢s imposition of external barriers (namely, the ââ¬Å"fortress Europeâ⬠tendany) are imposing upon those nationals of third parties from stepping into Europe unless they are related to a citizen of the EU who excerts their right to free movement. The EU has long been attacked as an exclusionary organisation concerned solely with the citizens of its own member states at the cost of non-EU citizens residing in the EU, even though many of the latter form part of ethnic or religious minorities and suffer social exclusion.[8] So, it seems that the principles governing the borders of the Community are failing those third party nationals.[9] The ââ¬Å"Outsidersâ⬠A vivid example of how ââ¬Å"fortress Europeâ⬠had imposed this restriction can be noted prior to the accession in 2004 of many, now, Central and Eastern European countries. Lavenex[10] argues that prior to, and with suggestions of accession for Central and Eastern European countries the, then, current members of Europe had feared large-scale immigration from these countries into their own territories. The EUââ¬â¢s already heavily regiinented rules of external border barriers on trade and migration from ââ¬Å"outsidersâ⬠(those countries not members of the EU) where to form part of the accession policies. Meaning that the acceeding Central and Eastern European countries encountered stringent preventative stances to their entrance into the EU on beahlf of the Community. But during a time when security at an intergovernmemtal level is already on red alert due to heightened tensions caused by the threat of terrorism,[11] it appears that migration has become a security rather than economic issue. So risking mmigrants and asylum-seekers being portrayed as a challenge to the protection of national identity and welfare provisions. Moreover, supporting the political construction of migration as a security rather than economic issue.[12] Getting in or staying out? The treatment of third country nationals (besides those who have derived rights through Community family members) can be understood through external and internal dimensions. The external element, namely the issue of ââ¬Å"getting into the EUâ⬠focuses on the member staes and the institutions emphasis of immigration and border controls. Yet, according to the case of Wijsenbeck[13], the member states are still able to perfomr checks at their own borders, be them external or not. But this policing of movement draws attention to the vulnerablity of the third country national.[14] But progression has been felt. Through Artcles such as K.1 to K.9 of the TEU governing policies such as asylum, immigration and third country nationals which have now been intergrated into the EC Treaty (as Title IV) , as well as Regulations have now inacted the uniform format for visas.[15] Regulations also cover the listings of third countries whose nationals must be on possession of visas when crossing external borders.[16] Importanly, the area of immigartion and the member statesââ¬â¢ stance on the matter of border control is liable to change in accordance with their political climate. The emphasis post-September 11th has fallen squarely on matters of security.[17] Various member states have also expressed concern at the numbers of third country nationals seeking asylum in their territory, so reinforcing their diffculties in gaining access into the EU. The internal dimension of the matter is one which concentrates on the rights of third country nationals already residing within the Community. As there is no stringent source as to their status upon this; such limiteed rights are based on various possible provisions. This can include their capacity as a family member of an EU citizen (as aforementioned) or as employees of EC service providers or as subject to one of the Communityââ¬â¢s Assocaition, Co-operation or other International Agreements with third countries.[18] Even though their residence in the EU may be legitimate the general range of EC rights and freedoms, however, do not apply to them. With speculation increasing as to the possible imposition of ID cards within the UK has also been backed by the controversial possible introduction of the staus of European citizenship. This citizenship, which would be conditional upon the possession of member state nationality, may only serve to emphasise the differences in treatment between EU nationals, who possess such nationality, and those who do not. But from an economic standpoint, countries potentially out of the line of terrorist fire have welcomed the idea of third country nationals, especially those intending to work, as being a potential boost to their economy. Yet the richer member states argue that the heightened security risks and ââ¬Å"flood gateâ⬠effects that recent accession has had is already having an adverse effect on their economies. Concluding Staying stationaery or moving through the times? But Peers[19] argues that change may soon be on the horizon with the implementation of Directive 2003/109 on the status of long-term resident third-country nationals within the European Union. This Directive was an opportunity to address the long-standing criticism that the EU gives insufficient protection to its resident third country nationals. Already being reported as limited and disappointing in a number of respects. Yet, if consequential jurisprudence reflects its interpretation as being in line with the context and objectives of the Directive, it could make a positive contribution to the status of third country nationals in the EU. This especially as in regards to movement between member states.[20] By common accord, the unity the EU claims for itselff when constituting itself as an ââ¬Å"area of freedomn, secrutiy and justiceâ⬠has become troublesome. Critics are quick to point out that the area in which freedom, security and justice are to reign is a ââ¬Å"spurious geographical unityâ⬠.[21] Yet, even if it were to be accepted that Europe is a geographical union, the fact remains that the EU has agreements with countries outside of this territory (such as the 1963 Ankara Agreement with Turkey), meaning that EU extends its reach outside of this area.[22] One of the main arguments behind the impact Europe is having by ââ¬Å"sealing offâ⬠its border lies closer to home. Given that accession into the Community is based upon adaptation of national policies, be them economic, political or social, to those already established within the EU, many countries faced closing their borders to the outside for upholding the principles of preventing illegal immigration. But, in contrast to this member states are also expected to uphold the humanitarian standards of refugee protection[23] and the principles of the European Human Rights Act. With the EU being a figure-head in the creation and implementation of human rights agendas, this contradiction will only serve to weaken the EUââ¬â¢s leading political status. Where member states face penalties for failing to uphold either of these policies, many are at a loss as to which one prevails. These conflicting ideals have obviously affected the manner in which those member states with borders to the ââ¬Å"outsideâ⬠have integrated the principles into their immigration and refugee procedures. Further to Lavenexââ¬â¢s idea of fear of mass migration by the West, Huysmans alleged that the question of migration from countries external to the EU is a security problem rather than just one of immigration and asylum. As Huysmans states: ââ¬Å"Since the 1980s, the political construction of migration increasingly referred to the destabilizing effects of migration on domestic integration and to the dangers for public order it implied.â⬠[24] Huysmans also alleged that due to such developments as the Schengen Agreements and the Dublin Convention ââ¬Å"â⬠¦visibly indicate that the European integration process is implicated in the development of a restrictive migration policy and the social construction of migration into a security question.â⬠This meaning that access for third country nationals is now even tougher maybe the member states would prefer for the barriers surronding ââ¬Å"fortress Europeâ⬠to reamin? The Schengen Convention completely removed border controls and placed stricter contorls at the external barrier of the EU. This resulting in a stronger emphasis on external restrictions and lifting all restirtcions between member states. The Schengen scheme had been directly accredited to concerns over the increase of organised crime within the Coimmunity. But with conerns inceasing still as to the problems of human and drugs trafficking into the EU from third countries and its threat to internal security only serves to push the issue of external border control into the spotlight once again. Ultimately, academic writing[25] has contemplated the responsibility of the EU to uphold itââ¬â¢s policy on human rights and itââ¬â¢s prevention of internal barriers to freedom of movement. But as inportant as thiese priniples may be in maintaining structure and authority the Community should also reconsider itââ¬â¢s position on a global scale when encountering the needs of asylum seekers at their external borders as well as those already residing with them without the claim of derived rights. Footnotes [1] Carrerra, S. (2005) [2] Peers, S. Towards Equality: Actual and Potential Rights of Third Country Nationals in the Euroepan Union. (1996) [3] Craig, P and De Bà ºrca, G. EU Law: Text, Cases and Materials. [4] Binkman, G (2004) [5] op cit [6] I bid 3 [7] Case 321/87 Commission v Belgium (1989) ECR 997 [8] Peers, S. (2004) [9] ECRE (2004) [10] Lavenex, S. Safe Third Countries: Extending the Eu Asylum and Immigration Policies to Central and Eastern Europe [11] Levy (2005) [12] Huysmans (2000) [13] (1999) [14] I bid 3 [15] Reg. 334/2002 [16] Reg. 359/2001 [17] I bid 11 [18] I bid 2 [19] I bid 8 [20] op cit [21] Lindahl, H. Finding a Place for Freedom, Security and Justice: The European Unionââ¬â¢s claim to Territorial Unity. (2004) [22] ibid 8 [23] I bid 10 [24] Huysmans (2002) [25] I bid 21
Thursday, September 19, 2019
Knowledge Management and Instructional Technology Essay -- Knowledge M
Knowledge Management and Instructional Technology The new "buzz word" in many corporate circles currently is the term "Knowledge Management or K.M." KM is considered mostly a role for the Information Technologist because of its storage of the company's information on databases. Because of the "info-glut" that is occurring in many corporations, K.M. is strongly becoming the role for the Instructional Technologist to group that information into training modules for the corporate Intranet, so that the corporation's employees can retrieve the "knowledge" in a real-time, need-to-know basis. In this white paper, I will define Knowledge Management from a business and an educational perspective. I will also discuss two basic strategies for Knowledge Management and the role the Instructional Technologist will have in the process. What is Knowledge Management? From the business perspective, the definition of Knowledge Management from the Business College of the University of Texas is The systematic process of finding, selecting, organizing, distilling, and presenting information in a way that improves an employee's comprehension in a specific area of interest. Knowledge management helps the organization to gain insight and understanding from its own experience. Specific Knowledge Management activities help focus the organization on acquiring, storing and utilizing knowledge for such things as problem-solving, dynamic learning, strategic planning and decision making (1998). In the article "Intellectual Capital and You" in Training Magazine, Knowledge Management is defined as " An effort to capture or tap an organization's collective experience and wisdom- including the tacit know-how that exists in people's head... ...eved September 17, 1999 from EBSCO Business Search on the Galileo: http://www.galileo.gsu.edu. Gordon, J. (1999). The whole enchilada: intellectual capital and you. Training Magazine Retrieved on September 13, 1999 from Training Supersite: http: //www.trainingsupersite.com/publications/magazines/training/909cover.htm Hansen, M., Nohria, N. & Tierney, T. ( 1999, March-April). What's your strategy for managing knowledge? Harvard Business Review, reprint 990206 Mudge, A. (1999, April-May). Knowledge Management: Do we know that we know? Communication World, (16)5, Retrieved on September 17, 1999 from EBSCO Business Search: http://mariner.galileo.gsu.edu Van Buren, M. (1999, May). A yardstick for knowledge management, Training & Development, (53)5 pp. 71+ Retrieved on September 17, 1999 from EBSCO Business Search on Galileo: http://mariner.galileo.gsu.edu
Wednesday, September 18, 2019
Feminism in Sylvia Plaths The Bell Jar :: Feminism Feminist Women Criticism
Feminism in The Bell Jar In Sylvia Plath's autobiographical novel The Bell Jar, the reader learns of the adventures of a young woman in a male-dominated society that will not let her achieve her true potential. Plath's alter ego, Esther, is thus driven to a nervous breakdown and attempts suicide numerous times. In many ways, this novel is a feminist text, centered around the struggles of a young woman who cannot reach her goals in our male-dominated society. People close to Esther, do not accept her talents as a poet and writer, but rather try to push her into traditionally more feminine roles. For example, Esther's mother repeatedly tries to convince her to learn shorthand, but Esther rebels, saying "...when I tried to picture myself in some job, briskly jotting down line after line of shorthand, my mind went blank." (100) Esther, unlike many women of her time, refuses to be controlled by society's gender-based constraints: "The last thing I wanted was infinite security and to be the place an arrow shoots off from. I wanted change and excitement and to shoot off in all directions myself, like the colored arrows from a Fourth of July rocket." (68) The phrases "infinite security" and "the place an arrow shoots off from" come from Mrs. Willard's description of the woman's role in society (58). This passage directly addresses Plath's central purpose in the novel, which is to look at the mental problems that can befall a woman with ambitions that the surrounding culture will not allow her to fulfill. This book was published in 1963, towards the beginning of the "feminist movement"; the events chronicled in this book, however, take place in 1953 (208), in a period during which women's rights were not yet widely recognized in our society. The passage quoted above, and the emotions which it conveys, are typical of a feminist like Esther, but Esther is ahead of her time and is thus unable to express herself to society in the way she wants.
Tuesday, September 17, 2019
The William Wrigley Jr. Company Essay
1.0 à Introduction Identifying opportunities for corporate financial restructuring was typical for Blanka Dobrynin, a managing partner of the hedge fund Aurora Borealis LLC. In 2002, with the then debt free William Wrigley Jr. Company (Wrigley) in her sights, she asked her associate Susan Chandler to conduct research on the impact of a $3 billion debt recapitalisation on the company. This case report aims to make an informed recommendation on whether Wrigley should pursue the $3 billion debt proposal. 2.0 Optimal Capital Structure According to Miller and Modiglianiââ¬â¢s (1958) first proposition, the value of a firm is independent of its capital structure, assuming no corporate taxes. It was later demonstrated that the existence of debt in the capital structure creates a debt shield that increases the value of the firm by the present value of the tax shield (Miller & Modigliani, 1963). This line of reasoning implies that debt financing adds significant value to the firm and an optimal capital structure occurs with 100% debt. However, this is an unlikely outcome in reality with restrictions imposed by lending institutions, bankruptcy costs and the need for preserving financial flexibility implying that management will maintain a substantial reserve of borrowing power (Miller & Modigliani, 1963). These imperfections have since been discussed as additional factors when determining an optimal capitalà structure. The trade off theory suggests that an optimal capital structure may be achieved by determining the trade-off between tax shields and the costs of financial distress (Kraus & Litzenberger, 1973). The presence of tax shields means that the optimal capital structure decision is unique for each firm (DeAngelo & Masulis, 1980). High levels of debt can lead to indirect bankruptcy costs and financial distress costs which relate generally the costs associated with going bankrupt or avoiding bankruptcy. At high debt levels, the benefit of debt may be offset by financial distress costs. It appears that the optimal cash structure exists somewhere in the middle. Jensen and Meckling (1976) noted the existence of ââ¬Ëagency costs of debtââ¬â¢. These costs arise when equity holders act in their own interest rather than the firmââ¬â¢s interest. As Wrigley is a family owned company it is unlikely that agency costs will be an issue. 3.0 Weighted Average Cost of Capital (WACC) The question that underlies the decision to pursue the debt proposal is whether Wrigley is efficiently financed without debt. In this report, the WACC will be the main factor when determining whether Wrigley is efficiently financed. The WACC is the minimum return that a company needs to satisfy all of its investors, which is also the ââ¬â it is the required rate of return on the overall firm. The value of Wrigley will be maximized when its WACC is minimized. This report will examine the optimal capital structure as the one that produces the lowest possible WACC. WACC is one of the most important methods in assessing a companyââ¬â¢s financial health, both for internal use, such as capital budgeting, and external use, such as valuing investments or companies. It is able to provide an insight into the cost of financing and can be used as a hurdle rate for investment decisions. It can also be used to find the best capital structure for the company. The WACC can be used as a rough guide to the interest rate per monetary unit of capital (Pratt & Grabowski, 2008). The WACC method can be considered a better indicator than other methods such as earnings per share (EPS) or earnings before interest and tax (EBIT) because it takes into consideration the relative weight of each component of a companyââ¬â¢s capital structure (Armitage, 2005). The calculation uses the market values of the components rather than the book values as these values may differ significantly. The components WACC takes into consideration include internal and external factors such as equity, debt, warrants, options, pension liabilities, executive stock options and government subsidies (Hazel, 1999); whereas the EPS and EBIT calculations only take into consideration the internal factors, such as total earnings. of the company and However, the earnings reported by a company may not be a reliable value, as they tend to report more favourable values as opposed to the true amounts. However, as the WACC is calculated according to M&M theory, some of the input parameters can be difficult to ascertain. This is due to the uncertainty that exists in the market that would influence the outcome. Another issue limitation with the WACC, is that it relies on the assumption made in the M&M propositions, which do not necessarily apply in the real world. Some assumptions that do not apply include the fact that transaction costs exist and individuals and corporations do not borrow at the same rate. Referring to Appendix 1, the calculations show a slight increase in the WACC after the $3 billion debt is acquired. This change is more profound when using the 10 year US treasury rate as the risk free return ââ¬â an increase from 10.11% to 10.28% for the WACC. Therefore it appears that the optimal capital structure for Wrigley would be one containinginclude no debt as this provides the lowest WACC. 4.0 Estimating the effect of the recapitalisation on: 4.1 Share value In an efficient market, it is assumed that the share price will changeà quickly to reflect investors changing perceptions about the new debt issue. The effect of the recapitalisation on the share price can be summarised by Miller and Modiglianiââ¬â¢s adjusted NPV formula: Post-recapitalisation equity value = Pre-recapitalisation equity value + Present value of debt tax shields + Present value of distress related costs + SignalingSignalling, incentive & clientele effects Assuming the debt will continue into perpetuity, the present value of the $3 billion debt would be $1.2 billion. Using the post recapitalisation value of equity incorporating the tax shield of $1.2 billion, the stock price is increased from $56.37 to $61.51. The remaining factors of this equation are very difficult to ascertain. The present value of the distress related costs could be assumed to be the value of a put option on the debt. Nevertheless, it could be assumed that financial distress costs would be negligible in Wrigleyââ¬â¢s situation, as it is a market leader with a strong financial position. It is very difficult to estimate the cost of signalingsignalling and clientele effects and it is necessary to bear this in mind when looking at the increase on share price as it does not fully reflect all relevant considerations. 4.2 Level of Flexibility Financial flexibility refers to the ability of a firm to respond in a timely and value-maximizing manner to unexpected changes in the firmââ¬â¢s cash flows or investment opportunity set (Dennis, 2011). Chief Financial Officers surveyed by Graham and Harvey (2001) state that financial flexibility is the most important determinant of corporate capital structure (Graham and Harvey, 2001). A flexible capital structure can be achieved by preserving access to low-cost sources of capital. DeAngelo and DeAngelo (2011) argue that firms should optimally maintain low levels of leverage in most periods in order to be better equipped to cope with the adverse consequences of exogenous shocks. They also argue that firms should maintain low leverage and high dividend payouts in ââ¬Å"normalâ⬠periods in order to preserve the option to borrow or issue equity in future ââ¬Å"abnormalâ⬠periods characterised by earnings shortà falls and/or lucrative investment opportunities. The financial flexibility of Wrigley will be reduced as borrowing $3 billion now will lower their ability to borrow in the future if there are any lucrative investment opportunities or cope with any unexpected exogenous shocks to the market and themselves. 4.3 Mix of Debt and Equity Considerations have to be made when evaluating the recapitalisation of Wrigleyââ¬â¢s capital structure by adding debt. A concern of Wrigley is deciding the debt ratio which optimizes the overall value of the firm. Companies are often inclined to choose debt over equity as the cost of debt is cheaper due to the tax shield created. With the addition of $3 billion of debt in Wrigleyââ¬â¢s capital structure, the tax shields benefit will increase the equity value by $1.2 billion. The estimation of the tax benefits are assumed under the condition that Wrigley will maintain debt value of $3 billion in perpetuity. As a result of $3 billion payout, the value of equity will decline by $1.8 billion which will be offset by the present value of the debt tax shield ($1.2 billion). Wrigleyââ¬â¢s debt/equity level after recapitalisation will be 78% and 22% debt. The traditional view is that taking on higher levels of debt could potentially generate more earnings on positive NPV projects which could increase the companyââ¬â¢s value. Although it should be noted that considerations have to be made at what which point, debt becomes more costly to Wrigley in terms of increased risk to shareholders. Assessing Wrigleyââ¬â¢s optimal debt level, it suggests that the optimal point would be not taking on any debt. By taking on debt, Wrigleyââ¬â¢s credit rating will fall from AAA to BB/B, as it would be increasing itââ¬â¢s risk levels of financial distress and risk of bankruptcy cost. Assessing From this, it can be recommended that Wrigleyââ¬â¢s optimal debt level, it suggests that the optimal point would be not taking on any debt.having minimal debt. 4.4 Reported earnings per share Before the proposed recapitalisation, Wrigley will have no minimal debt. If Wrigley does not have any income, they still need to pay the interest on the debt, so EPS will be negative. Referring to Appendix 2, the two lines intersect where EBIT is $1.70 billion and EPS is $12.21. This is the break-even point ââ¬â if EBIT is above this point leverage is beneficial. If Wrigleyââ¬â¢s income was higher than $1.70 billion, they could should take the $3 billion debt. In fact, the current income is only $0.51 billion therefore according to a breakeven EBIT analysis, Wrigley should not pursue the debt. 5.0 Other matters for the boardââ¬â¢s consideration 5.1 Effect on Voting Control Assuming the $3billion is used either for a dividend payout or share repurchase, only the second option would alter the amount of shares outstanding. The Wrigley family already controlled 21% of the common stock and 58% of the Class B common stock, which had superior voting rights attached. A $3 billion share repurchase would substantially increase the voting control of the Wrigley family, however the family was already in a majority position so voting control would not be substantially different. A strong controlling majority is highly advantageous in deterring potential mergers and acquisitions. 5.2 Clientele and Signaling effects In general, companies that take on debt signal to investors that the company is in a good financial position as it is able to make future interest repayments. If the debt were used for a dividend payout, this would signal to investors that the company is doing well and increase the stock price. However, using the debt for a share repurchase might have a clientele effectà on potential investors that prefer dividend payouts. These investors could potentially sell their remaining stock in reaction to the share buyback resulting in the stock price falling. 6.0 Conclusion The WACC indicated that taking on $3b of debt would reduce the value of Wrigley company. This value could change, provided the Wrigley company had an investment opportunity or plan to use the newly obtained debt of $3b. The WACC value may be disregarded or adjusted if Wrigley had a high NPV project to invest in or provided a specific use for the funds. However, in the current situation, there is no indication of the reasons for Wrigley to take on the debt and thus they are unnecessarily restricting their financial flexibility. This could prove costly in the future if there are any unexpected negative shocks to the market or Wrigley may miss out on a highly lucrative investment opportunity due to their inability to borrow more. Therefore it is our recommendation that the Wrigley company does not take on the $3b of new debt as it would reduce the total value of the company at this point in time. 7.0 References Armitage, S. (2005). The Cost of Capital: Intermediate Theory. Cambridge, UK: Cambridge University Press. DeAngelo H., & DeAngelo, L., (2006) Capital Structure, Payout Policy, and Financial Flexibility, University of Southern California working paper. DeAngelo, H., & R.W. Masulis. (1980) Optimal Capital Structure under Corporate and Personal Taxation. Journal of Financial Economics 8, 3-29. DeAngelo, H., DeAngelo, L., & Whited T.M., (2011) Capital structure dynamics and transitory debt. Journal of Financial Economics, 99, 235ââ¬â261. Denis, D J. (2011) Financial Flexibility and Corporate Liquidity. Journal of Corporate Finance, 17(3), 667-674. J.R. Graham, & C.R. Harvey., (2001) The theory and practice of corporate finance: evidence from the field. Journal of Finance and Economics 60, 187ââ¬â243. Jensen, M., & Meckling, W. (1976). Theory of the firm: Managerial behavior, agency costs, and ownership structure. Journal of Financial Economics 3, 305-360. Johnson, H. (1999). Determining Cost of Capital: The Key to Firm Value. London: FT Prentice Hall. Kraus, A., & R.H. Litzenberger. (1973) A State Preference Model of Optimal Financial Leverage. Journal of Finance (September), 911-922. Modigliani, F., & M.H. Miller. (1958). The Costs of Capital, Corporate Finance, and the Theory of Investment. American Economic Review, 48 (June), 261-297. Modigliani, F., & M.H. Miller. (1963). Corporate Income Taxes and the Cost of Capital: A Correction. American Economic Review 53 (June), 433-443. Pratt, Shannon P., & Roger J. Grabowski. (2008) Cost of Capital: Applications and Examples. Hoboken, NJ: Wiley.
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